IB Biology HL D3.1 Reproduction Questions

Practise IB Biology HL D3.1 with evidence-led questions on gamete formation, fertilization, reproductive hormones, pregnancy, development and contraception.

148 questions in this syllabus scope, with question parts counted together.

Syllabus
First assessment 2025
Course
Biology HL
Level
HL

Exam analysis

HL · 2010–2025
Papers with this topic63 / 117in the analysed sample
Latest appearanceNovember 2025
Tagged question parts121
Paper types5

Most tested objectives

  1. D3.1.14 (HL)—Gametogenesis18 papers
  2. D3.1.12—Seed dispersal and germination16 papers
  3. D3.1.8—Sexual reproduction in flowering plants15 papers
  4. D3.1.17 (HL)—Pregnancy testing12 papers
  5. D3.1.15 (HL)—Preventing polyspermy10 papers

Common question formats

  • Definition or recall
  • Diagram interpretation
  • Process explanation
  • Comparison
  • Evaluation
  • Experimental design
  • Graph interpretation

Recent exam appearances

November 2025Paper 1A HL · TZ3Q29, 30[ 2 ]
November 2025Paper 1A HL · TZ1Q29[ 1 ]
May 2025Paper 2 HL · TZ3Q8(a)[ 4 ]

117 papers analysed · Tagging incomplete

Exam points

  • Compare asexual clones with sexual reproduction; link meiosis and gamete fusion to ploidy and variation.
  • Identify human reproductive structures from diagrams and explain their functions.
  • Interpret ovarian and uterine hormone graphs and explain FSH/LH feedback.
  • Explain fertilisation from acrosome penetration to nuclear fusion and the cortical block to polyspermy.
  • Sequence IVF from FSH treatment and egg collection to embryo culture and transfer.
  • Identify floral structures and infer haploid meiotic products in anthers.
  • Trace pollen-tube growth to fertilisation and relate insect-flower adaptations to pollen transfer.
  • Explain how dioecy and self-incompatibility promote cross-pollination and reduce inbreeding.
  • Link seed dispersal to reduced competition; trace water, gibberellin and amylase in germination.
  • Trace hypothalamic GnRH through pituitary FSH/LH to sex-hormone production at puberty.
  • Compare spermatogenesis and oogenesis using meiotic stages, ploidy and cell outputs.
  • Trace blastocyst formation and implantation; explain HCG tests and corpus-luteum maintenance.
  • Explain placental exchange and pregnancy hormones; trace oxytocin-prostaglandin feedback in labour.

Exam points

  • Define a clone as genetically identical cells or organisms derived from one parent.
  • Predict high genome similarity in vegetatively propagated offspring, allowing for differences caused by mutation.

Question 1

[Maximum number: 1]

What is a definition of a clone?

A

A group of cells derived from a single parent cell

B

Differentiated cells that retain the capacity to divide

C

A fetus developed specifically for medical use

D

A group of cells that have lost the ability to differentiate

Exam points

  • Explain how meiosis halves chromosome number and fertilization restores diploidy between generations.
  • Explain how meiosis and fertilization combine parental alleles to produce variation.

Question 1

[Maximum number: 1]

Which cell is a polyploid zygote produced by fusion of one haploid and one diploid gamete?

A
Figure for Question 1 — IB Biology HL — Option A
B
Figure for Question 1 — IB Biology HL — Option B
C
Figure for Question 1 — IB Biology HL — Option C
D
Figure for Question 1 — IB Biology HL — Option D

No public sample questions are available for this syllabus point yet.

Exam points

  • Draw and label the adult male reproductive system, placing testes, ducts, glands, urethra and penis correctly.
  • Relate the epididymis to sperm storage, final maturation and the acquisition of motility.

Question 1

[Maximum number: 1]

The diagram shows the human female reproductive system.

Figure for Question 1 — IB Biology HL

What is produced by structure X ?

A

FSH

B

X chromosomes

C

Fertilized eggs

D

Estrogen and progesterone

Exam points

  • Explain how FSH and LH link follicle growth to ovulation and corpus luteum formation.
  • Relate oestradiol and progesterone feedback to endometrium build-up and menstruation.

Question 1

[Maximum number: 1]

What event occurs approximately at the time of the dotted line (time X )?

Figure for Question 1 — IB Biology HL
A

Menstruation

B

Ovulation

C

Development of the primary follicle

D

Implantation

Exam points

  • Describe sperm reaching and entering the egg during human fertilization.
  • Identify breakdown of sperm and egg nuclear membranes during human fertilization.

Question 1

[Maximum number: 6]

Describe the process of fertilization in humans.

Exam points

  • Explain how FSH injections stimulate multiple follicles during IVF.
  • Outline IVF from egg collection and in-vitro fertilization through embryo culture and transfer to the uterus.

Question 1

[Maximum number: 1]

For what reason are daily FSH injections given during IVF treatment?

A

To suppress the natural menstrual cycle

B

To induce the ovary to produce more eggs than normal

C

To prepare the lining of the ovary for embryo transfer

D

To prevent the development of multiple embryos

Exam points

  • Identify anthers, stigmas, ovaries and ovules, and locate male and female gametes in pollen and ovules.
  • Distinguish pollen transfer from anther to stigma (pollination) from fusion of male and female gametes (fertilization).
  • Trace the pollen tube to the ovule, then link fertilization with embryo formation inside the seed.

Question 1

[Maximum number: 1]

The diagram shows a cross-section of a flower.

Figure for Question 1 — IB Biology HL

What describes the structure labelled Z ?

A

Structure Z is the anther, which is part of the stamen.

B

Structure Z is the stigma, which is part of the stamen.

C

Structure Z is the anther, which is part of the carpel.

D

Structure Z is the stigma, which is part of the carpel.

Exam points

  • Explain how nectar or sugary secretions attract insect pollinators, increasing the chance of pollen transfer.
  • Identify sticky pollen and specific floral odours as adaptations that support insect pollination.

Question 1

[Maximum number: 1]

The drawing shows a flower of red valerian, Centranthus ruber.

Figure for Question 1 — IB Biology HL

Structure IV contains a gland that secretes a sugary liquid. Suggest a benefit to the plant of secreting this liquid.

Exam points

  • Identify dioecy—plants with separate male and female individuals—as a mechanism that promotes cross-pollination.

Question 1

[Maximum number: 1]

Flowering plants can use either self-pollination or cross-pollination when they carry out sexual reproduction. Which plants are most likely to cross-pollinate?

A

Plants that are hermaphrodites

B

Plants whose anthers and stigmas mature at the same time

C

Plants with flowers that have much longer stamens than stigmas

D

Plants that are either male or female

Exam points

  • State that self-incompatibility alleles prevent inbreeding.

Exam points

  • Explain how seed dispersal reduces competition with the parent plant and spreads offspring away from it.
  • State that germination requires water, oxygen and a suitable temperature.
  • Trace water uptake, gibberellin production, amylase activation and soluble sugar movement from cotyledon reserves to the growing embryo.

Question 1

[Maximum number: 3]

The image shows a cell in the anther of a lily (Lilium sp.) plant during the first division of meiosis.

Figure for Question 1 — IB Biology HL

Question (a)

(a)

The diagram shows a cross section through a broad bean (Vicia faba) seed.

Figure for Question (a) — IB Biology HL
[ 3 ]

Question (i)

(i)

On the diagram, label the cotyledon.

[ 1 ]

Question (ii)

(ii)

Outline the function of the cotyledon.

[ 2 ]

Exam points

  • Explain how hypothalamic GnRH triggers pituitary LH release and how LH increases sex-hormone production during puberty.

Question 1

[Maximum number: 1]

What controls the developmental changes during puberty?

I. Increased release of gonadotropin-releasing hormone (GnRH) by the hypothalamus
II. Luteinizing hormone (LH) leading to increased sex hormone production
III. Gonadotropin-releasing hormone (GnRH) triggering the onset of increased luteinizing hormone (LH)

A

I and II only

B

I and III only

C

II and III only

D

I, II and III

Exam points

  • Describe how spermatogenesis produces four sperm through equal meiotic divisions and differentiation.
  • Compare gametogenesis outcomes: equal cytokinesis produces four sperm, while unequal cytokinesis produces one ovum and polar bodies.

Question 1

[Maximum number: 1]

Gametogenesis produces sex cells for sexual reproduction.

What distinguishes oogenesis from spermatogenesis in humans?

A

The first meiotic division starts at puberty.

B

Mitosis produces many cells for gametogenesis.

C

Unequal division of cytoplasm occurs at cytokinesis.

D

Haploid gametes are produced at the end of meiosis II.

Exam points

  • Explain how acrosome enzymes digest the zona pellucida and allow one sperm to reach or penetrate the egg membrane.
  • Explain how cortical-granule release changes the zona pellucida or egg membrane to block polyspermy.
  • Sequence the acrosome reaction, sperm-egg fusion/penetration and cortical reaction during normal fertilization.

Question 1

[Maximum number: 1]

The diagram shows the location of the zona pellucida, a layer of glycoproteins on the human ovum.

Figure for Question 1 — IB Biology HL

What is the main function of the zona pellucida?

A

To prevent polyspermy

B

To form polar bodies

C

To provide amino acids

D

To release FSH

Exam points

  • Identify a blastocyst as a hollow ball of cells.

Question 1

[Maximum number: 1]

What is a blastocyst?

A

An unfertilized egg surrounded by follicle cells

B

An unfertilized egg cell expelled by menstruation

C

The follicle when it has swelled up with fluid

D

The embryo when it has become a hollow ball of cells

Exam points

  • Explain that the early embryo or blastocyst secretes HCG after implantation.
  • Link HCG to maintenance of the corpus luteum and continued progesterone support of the endometrium.
  • Explain that pregnancy tests use monoclonal antibodies to detect HCG.

Question 1

[Maximum number: 1]

What is used in a pregnancy test kit?

A

Monoclonal antibodies against hybridoma cells

B

Antibodies against monoclonal hybridoma cells

C

HCG produced by plasma cells fused with tumour cells

D

Monoclonal antibodies produced by hybridoma cells against HCG

Exam points

  • Explain how placental villi and close maternal/fetal vessel proximity provide large surface area and short diffusion distance for exchange.
  • Describe transport of gases, nutrients, wastes and antibodies between maternal and fetal circulation without blood mixing.
  • Relate placental structure and hormone production to maintenance of pregnancy.

Question 1

[Maximum number: 1]

Which statement applies to the placenta?

A

Carbon dioxide diffuses from fetus to mother across the placenta.

B

Maternal and fetal blood mix at the placenta.

C

If an ovum is not fertilized the placenta is lost during menstruation.

D

The umbilical cord connects the placenta to the mother's abdomen.

Exam points

  • Explain how progesterone maintains the endometrium and suppresses FSH/LH during pregnancy.
  • Trace oxytocin positive feedback in childbirth: contractions trigger further oxytocin release and stronger uterine contractions.

Question 1

[Maximum number: 1]

The diagram shows the position of the fetus at childbirth.

Figure for Question 1 — IB Biology HL

Which hormone stimulates contractions of muscle cells in the region labelled X ?

A

Estrogen

B

Oxytocin

C

Progesterone

D

Thyroxin

No public sample questions are available for this syllabus point yet.